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Domain definition and target classification for CASP6
Author(s) -
Tress Michael,
Tai ChinHsien,
Wang Guoli,
Ezkurdia Iakes,
López Gonzalo,
Valencia Alfonso,
Lee Byungkook,
Dunbrack Roland L.
Publication year - 2005
Publication title -
proteins: structure, function, and bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.699
H-Index - 191
eISSN - 1097-0134
pISSN - 0887-3585
DOI - 10.1002/prot.20717
Subject(s) - domain (mathematical analysis) , computer science , artificial intelligence , mathematics , mathematical analysis
Assessment of structure predictions in CASP6 was based on single domains isolated from experimentally determined structures, which were categorized into comparative modeling, fold recognition, and new fold targets. Domain definitions were defined upon visual examination of the structures with the aid of automated domain‐parsing programs. Domain categorization was determined by comparison of the target structures with those in the Protein Data Bank at the time each target expired and a variety of sequence and structure‐based methods to determine potential homologous relationships. Proteins 2005;Suppl 7:8–18. © 2005 Wiley‐Liss, Inc.