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Immunoglobulin‐producing cells in human prostate
Author(s) -
Bene M. C.,
Studer A.,
Faure G.
Publication year - 1988
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990120202
Subject(s) - prostate , antibody , medicine , immunoglobulin g , immunology , pathology , biology , cancer
Immunohistological techniques were used to investigate the presence of immunoglobulin‐producing cells in human prostate. Surgical samples from 14 patients with prostate hyperplasia were analyzed. Lymphoid infiltration was rarely seen and was in no way comparable with the classical structure of mucosae‐associated lymphoid tissue (MALT). Plasma cells were observed in nine cases. They produced predominantly IgA and lambda chains, but noticeable numbers of IgM‐secreting cells were also seen. These cells were most numerous in patients with antecedents of infection or prostatitis. These data suggest that the local immune system of the prostate is in relation with the MALT, and can be colonized by MALT‐derived cells in response to bacterial stimuli.