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Embryonal hyperplasia of the prostate
Author(s) -
Bennett Betsy D.,
Gardner William A.
Publication year - 1985
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990070409
Subject(s) - hyperplasia , prostate , pathology , medicine , basal (medicine) , adenocarcinoma , cancer , insulin
Abstract Unusual patterns of prostatic hyperplasia require close scrutiny by the pathologist in order to distinguish them from adenocarcinoma. One such pattern, basal cell hyperplasia, has been the subject of several recent reports. We describe a second pattern, which we refer to as embryonal hyperplasia because of its resemblance to the embryonal or fetal prostate. Although this lesion bears some resemblance to basal cell hyperplasia, it differs in histochemical characteristics. A review of previous cases of this entity, which were reported as basal cell hyperplasia, suggests that they differ in ultrastructural characteristics as well. The significance of this proliferative pattern currently rests in its resemblance to prostatic adenocarcinoma, particularly when present in many chips from a transurethral resection of the prostate. Further studies, especially relating to hormone dependency, would be useful in understanding the development of this and other more atypical prostatic proliferations.