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A model of an intraprostatic vas deferens in the rat
Author(s) -
Bazer Gary T.,
Knight David S.
Publication year - 1983
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990040110
Subject(s) - vas deferens , medicine , prostate , urology , pathology , endocrinology , cancer
The study of the effect of hormones in seminal fluid upon prostate tissue is hampered by the lack of a suitable model. Such a model is described in this paper, and its possible usefulness is discussed. The vas deferens of the rat is moved from its normal position into a surgical incision into the ventral prostate. Squamous metaplasia of epithelium in prostatic acini at early stages is replaced by cuboidal epithelium. At later stages, normal‐appearing glandular epithelium is seen as close as 50μm to the vas deferens. The structure of the vas deferens is not affected.