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Effect of molybdate on androgen receptor levels in canine prostate
Author(s) -
Naritoku Wesley Y.,
Howard Edwin B.,
Britt James O.,
Markland Francis S.
Publication year - 1982
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990030610
Subject(s) - sodium molybdate , molybdate , androgen receptor , prostate , receptor , androgen , endocrinology , medicine , chemistry , prostate cancer , biology , hormone , inorganic chemistry , cancer
A comparative study on the stabilizing effect of sodium molybdate on androgen receptors was performed using canine prostates. Prostates from intact male dogs of mixed breeds were run in parallel sucrose density gradient analyses, using buffer systems with or without molybdate. Prostates that were homogenized in a molybdate buffer showed a significant increase in androgen receptor content relative to those in a molybdate‐free system.