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Squamous metastases from prostatic adenocarcinoma
Author(s) -
Accetta Peter A.,
Gardner William A.
Publication year - 1982
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990030510
Subject(s) - adenocarcinoma , prostatic adenocarcinoma , medicine , prostatic acid phosphatase , pathology , immunoperoxidase , carcinoma , basal cell , prostate , staining , oncology , cancer , immunology , antibody , monoclonal antibody
Two patients with prostatic adenocarcinoma are reported whose metastases harbored large foci of squamous cell carcinoma. The prostatic origin of such areas was proven by immunoperoxidase staining for prostatic acid phosphatase (PAP) as well as the identification of transition zones between adenocarcinoma and squamous cell carcinoma. The possible role of estrogen therapy in inducing the squamous change is discussed.