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Effect of surgery and adjuvant chemotherapy on the R3327 MAT‐Ly Lu tumor
Author(s) -
Kadmon Dov,
Heston Warren D. W.,
Fair William R.
Publication year - 1981
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.2990020308
Subject(s) - medicine , lymphadenectomy , chemotherapy , lymph , primary tumor , adenocarcinoma , surgery , oncology , lymph node , metastasis , cancer , pathology
The R3327 MAT‐Ly Lu is a prostate derived, anaplastic, hormone independent carcinoma. It spreads primarily to regional lymph nodes, followed by lung metastases. Combination therapy with surgery (tumor removal with or without regional lymphadenectomy) and chemotherapy (ICRF‐159) was more effective treatment than either one alone. Primary tumor excision plus lymphadenectomy appeared to reduce the number of pulmonary metastases.