Premium
The 25th Annual Prostate Cancer Foundation Scientific Retreat Report
Author(s) -
Miyahira Andrea K.,
Soule Howard R.
Publication year - 2019
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.23872
Subject(s) - prostate cancer , cancer , prostate , medicine , oncology , management of prostate cancer , translational research , androgen receptor , cancer research , pathology
Background The 25th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held in Carlsbad, CA, from 26 to 28 October 2018. Methods The PCF Scientific Retreat is the foremost scientific research conference in the world that focuses on the most significant and promising recent advancements in basic, translational, and clinical prostate cancer research, as well as research from other fields that has substantial potential to advance prostate cancer research. Results The major topic areas discussed at this year's meeting included (a) new insights into prostate cancer biology and treatment; (b) approaches for accelerating precision medicine for prostate cancer; (c) prostate‐specific membrane antigen‐targeted therapy and imaging for prostate cancer; (d) updates on Poly (ADP‐ribose) polymerase (PARP)‐inhibitor clinical trial results; (e) the biology and role of prostate cancer stem cells; (f) new approaches for targeting the androgen receptor and other steroid hormone receptor pathways; (g) racial disparities in prostate cancer treatment and outcomes; (h) the role of the nervous system in prostate cancer development and progression; (i) the role of the WNT signaling pathway in normal prostate and prostate cancer biology; (j) novel immunotherapy approaches; and (k) the ecology of prostate cancer. Conclusions This article reviews the research presented by the speakers at the 2018 PCF Scientific Retreat for the purpose of disseminating this knowledge to the global research community and ultimately accelerating new understandings and treatment strategies for prostate cancer.