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Racial disparities in prostate cancer incidence rates by census division in the United States, 1999–2008
Author(s) -
Cook Michael B.,
Rosenberg Philip S.,
McCarty Frances A.,
Wu Manxia,
King Jessica,
Eheman Christie,
Anderson William F.
Publication year - 2015
Publication title -
the prostate
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 123
eISSN - 1097-0045
pISSN - 0270-4137
DOI - 10.1002/pros.22958
Subject(s) - prostate cancer , census , incidence (geometry) , medicine , prostate , cancer incidence , demography , cancer , gerontology , oncology , environmental health , population , physics , sociology , optics
BACKGROUND Black men have a higher incidence of prostate cancer than white men in the U.S., but little is known whether incidence or racial differences vary geographically. Understanding these differences may assist future studies on causes of prostate cancer. To address such, we leverage the unique resource of the National Program of Cancer Registries (NPCR) combined with Surveillance, Epidemiology and End Results (SEER). METHODS Prostate cancer counts and population denominators by race (black, white), age, calendar year, and U.S. census division, for the period 1999–2008, were extracted from NPCR and SEER. We calculated age‐standardized incidence rates (ASR) and estimated annual percent changes (EAPC) by race and census division. We assessed black‐to‐white incidence rate ratios (BWIRR) by census division and by calendar period. RESULTS This analysis included 1,713,471 prostate cancer cases and 1,217 million person‐years. Black ASRs ranged from 176 per 100,000 person‐years in Mountain division to 259 in Middle Atlantic. BWIRRs ranged from 1.20 in Western divisions to 1.72 in Southeastern divisions. EAPCs indicated that prostate cancer incidence is not decreasing in East South Central, unlike all other divisions. White EAPCs displayed similar variations by census division, resulting in modest temporal changes in BWIRRs. CONCLUSIONS Within the U.S., there exists significant geographic variability in prostate cancer incidence rates. Although there are large geographic differences in BWIRRs, temporal trends are fairly stable. This may indicate that primary factors affecting prostate cancer incidence rates vary geographically but affect both black and white men to a similar degree. Prostate 75: 758–763, 2015 . Published 2015. This article is a U.S. Government work and is in the public domain in the USA.