Open AccessRare case of subependymal giant cell astrocytoma without clinical features of tuberous sclerosis: Case report and literature review
Author(s) -
Azam Mohammad,
Rath Satyajeet,
Khurana Rohini,
Shukla Saumya,
Parween Ruhi
Publication year - 2017
Publication title -
precision radiation oncology
Language(s) - English
Resource type - Journals
ISSN - 2398-7324
DOI - 10.1002/pro6.24
Subject(s) - tuberous sclerosis , subependymal giant cell astrocytoma , subependymal zone , medicine , pathology , lesion , biopsy , angiofibroma , magnetic resonance imaging , radiology , dermatology , astrocytoma , glioma , cancer research
Subependymal giant cell astrocytoma (SEGA) is a slow‐growing tumor originating in the walls of the lateral ventricles, usually presenting in the first two decades of life, and is often associated with tuberous sclerosis complex. However, few cases of SEGA without any clinical features of tuberous sclerosis complex have been reported. Here, we present a case of an 11‐year‐old boy with right hemibody weakness and headache for 1.5 years. He was diagnosed with solitary SEGA without any clinical features of tuberous sclerosis complex. Magnetic resonance imaging of the brain showed an intracranial space‐occupying lesion in the left internal capsule. Biopsy was consistent with SEGA. There were no stigmata of tuberous sclerosis complex. The patient was treated with curative intent by radiotherapy.