Open AccessMultiple severe late adverse effects after definitive chemoradiation for locally advanced cervical cancer
Author(s) -
Danko Calida Marie,
Hong Linda Jahwa,
Slater Jerry Donald
Publication year - 2021
Publication title -
precision radiation oncology
Language(s) - English
Resource type - Journals
ISSN - 2398-7324
DOI - 10.1002/pro6.1126
Subject(s) - medicine , brachytherapy , chemoradiotherapy , cervical cancer , external beam radiotherapy , radiation therapy , adverse effect , disease , cancer , organ system , radiology , surgery , oncology
Concurrent chemoradiation is the standard of care for locally advanced cervical cancer and is commonly associated with mild to moderate toxicities. Severe late complications in multiple organ systems in patients without known patient‐ or treatment‐related risk factors are rare. A 42‐year‐old woman was treated with definitive chemoradiotherapy with external beam radiotherapy and brachytherapy. She had complete resolution of the disease, with no evidence of recurrence. However, she experienced late morbidity in multiple organ systems due to treatment, likely indicating an increased sensitivity to radiation. This case highlights the need for improvements in the identification of such patients.