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Publication year - 2021
Publication title -
protein science
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 3.353
H-Index - 175
eISSN - 1469-896X
pISSN - 0961-8368
DOI - 10.1002/pro.4163
Subject(s) - cover (algebra) , citation , computer science , process (computing) , information retrieval , computational biology , world wide web , biology , engineering , programming language , mechanical engineering
Non‐homologous end joining (NHEJ) as the primary conserved DNA double‐strand break repair process in human cells. NHEJ, more like a multi‐component, multifunctional engine, functions mechanistically for its coordinated movements, assembles, and regulation. Like the old car engine malfunctioning without a linchpin and flexible belt, the NHEJ efficiency arises from a flexible conformational control principle. The NHEJ components were matched on the SKODA 100 car engine built in 1973 in Czechoslovakia. See article by Hammel and Tainer, pp. 1735–1756 .
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