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CDtoolX, a downloadable software package for processing and analyses of circular dichroism spectroscopic data
Author(s) -
Miles Andrew J.,
Wallace B. A.
Publication year - 2018
Publication title -
protein science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.353
H-Index - 175
eISSN - 1469-896X
pISSN - 0961-8368
DOI - 10.1002/pro.3474
Subject(s) - circular dichroism , folding (dsp implementation) , synchrotron radiation , crystallography , software , protein folding , chemistry , materials science , computer science , physics , optics , engineering , biochemistry , programming language , electrical engineering
Circular dichroism (CD) spectroscopy is a highly used method for the examination and characterization of proteins, including, amongst other features, their secondary and tertiary structures, thermal stability, comparisons of wildtype and mutant proteins, and monitoring the binding of small molecules, folding/unfolding pathways, and formation of macromolecular complexes. This article describes CDtoolX, a new, user‐friendly, free‐to‐download‐and‐use software program that enables processing, displaying, archiving, calibrating, comparisons, and analyses of CD and synchrotron radiation circular dichroism spectroscopic data.