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Front Cover: Serum Small Extracellular Vesicles Proteome of Tuberculosis Patients Demonstrated Deregulated Immune Response
Author(s) -
Arya Rakesh,
Dabral Deepti,
Faruquee Hossain Md.,
Mazumdar Himangshu,
Patgiri Saurav Jyoti,
Deka Trinayan,
Basumatary Rumi,
Kupa Rukuweu,
Semy Chayale,
Kapfo Wetetsho,
Liegise Kevideme,
Kaur Inderjeet,
Choedon Tenzin,
Kumar Purnima,
Behera Rajendra Kumar,
Deori Pranjal,
Nath Reema,
Khalo Kerekha,
Saikia Lahari,
Khamo Vinotsole,
Nanda Ranjan Kumar
Publication year - 2020
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.202070011
Subject(s) - proteome , immune system , extracellular , microbiology and biotechnology , immunology , biology , chemistry , biochemistry
Quantitative proteome analysis of serum small extracellular vesicles isolated from healthy controls and drug naive active tuberculosis patients showed altered protein composition. A set of four important proteins (SERPINA1, KYAT3, HP and APOC3) showed deregulation. These important proteins are involved in neutralizing bacterial infection, psychotic symptoms, acute immune response and adipose tissue lipolysis. This is reported by Rakesh Arya, Deepti Dabral, Hossain Md. Faruquee, Himangshu Mazumdar, Saurav Jyoti Patgiri, Trinayan Deka, Rumi Basumatary, Rukuwe‐u Kupa, Chayale Semy, Wetetsho Kapfo, Kevideme Liegise, Inderjeet Kaur, Tenzin Choedon, Purnima Kumar, Rajendra Kumar Behera, Pranjal Deori, Reema Nath, Kerekha Khalo, Lahari Saikia, Vinotsole Khamo, Ranjan Kumar Nanda in article 1900062.