Premium
Front cover: Proteomic profiling of Gram‐negative bacterial outer membrane vesicles: Current perspectives
Author(s) -
Lee Jaewook,
Kim Oh Youn,
Gho Yong Song
Publication year - 2016
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.201670090
Subject(s) - bacteria , bacterial outer membrane , gram negative bacteria , microbiology and biotechnology , vesicle , biology , intracellular parasite , virulence , virulence factor , extracellular , escherichia coli , membrane , biochemistry , gene , genetics
DOI: 10.1002/prca.201600032 Outer membrane vesicles (OMVs) are extracellular vesicles derived from Gram‐negative bacteria. Recent studies implies that OMVs may function as intercellular communicasomes in bacteria‐bacteria and bacteria‐host interactions. For bacteria‐bacteria interactions, OMVs can mediate antibiotic resistance, nutrient acquisition, and killing competing bacteria. For bacteria‐host interactions, OMVs can play roles in proinflammatory responses, adhesion to host cells, and virulence factor delivery. Further details can be found in the article by Jaewook Lee et al. on page 897.