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Frontispiece: New insights on the mitochondrial proteome plasticity in Parkinson's disease
Author(s) -
Aroso Miguel,
Ferreira Rita,
Freitas Ana,
Vitorino Rui,
GomezLazaro Maria
Publication year - 2016
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.201670047
Subject(s) - mitochondrion , proteome , biology , organelle , proteomics , computational biology , disease , attribution , microbiology and biotechnology , neuroscience , evolutionary biology , bioinformatics , psychology , genetics , gene , pathology , medicine , social psychology
DOI: 10.1002/prca.201500092 Mitochondria are central organelles for neuronal cell physiology and survival, which malfunction has been linked to Parkinson's disease. Proteomics of enriched mitochondrial fractions followed by data integration and network analysis, taking in consideration variables such as model of PD, cell line or tissue origin highlight the modulation of several biological processes. This image was produced using images modified from Servier Medical Art (Servier, www.servier.com, licensed under a Creative Commons Attribution 3.0 Unported Licence). Further details can be found in the article by Miguel Aroso et al. on page 415.

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