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Elucidating the anti‐ Staphylococcus aureus antibody response by immunoproteomics
Author(s) -
Stentzel Sebastian,
Gläser Regine,
Bröker Barbara M.
Publication year - 2016
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.201600050
Subject(s) - staphylococcus aureus , immune system , priming (agriculture) , immunology , vaccination , antibody , microbiology and biotechnology , pathogen , acquired immune system , medicine , biology , bacteria , genetics , germination , botany
Staphylococcus aureus is a notorious pathogen both in‐ and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory, a key property of the adaptive immune system, is the basis of successful vaccination, immunoproteomics holds promise for paving the way to an effective S. aureus vaccine.