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A call for a fresh new look at the plasma proteome
Author(s) -
Hanash Samir
Publication year - 2012
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.201200052
Subject(s) - proteome , proteomics , plasma medicine , computational biology , data science , bioinformatics , computer science , biology , plasma , biochemistry , physics , gene , quantum mechanics , atmospheric pressure plasma
Serum and plasma from which serum is derived represent a substantial challenge for proteomics due to their complexity. A landmark plasma proteome study was initiated a decade ago by the H uman P roteome O rganization ( HUPO ) that had as an objective to examine the capabilities of existing technologies. Given the advances in proteomics and the continued interest in the plasma proteome, it would timely reassess the depth and breadth of analysis of plasma that can be achieved with current methodology and instrumentation. A collaborative project to define the plasma proteome and its variation, with a plan to build a plasma proteome database would be timely.