Premium
Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics
Author(s) -
Zhu Heng,
Cox Eric,
Qian Jiang
Publication year - 2012
Publication title -
proteomics – clinical applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 54
eISSN - 1862-8354
pISSN - 1862-8346
DOI - 10.1002/prca.201200041
Subject(s) - proteomics , protein microarray , dna microarray , computational biology , microarray , biomarker , identification (biology) , biology , bioinformatics , genetics , gene , gene expression , botany
Functional protein microarrays were developed as a high‐throughput tool to overcome the limitations of DNA microarrays and to provide a versatile platform for protein functional analyses. Recent years have witnessed tremendous growth in the use of protein microarrays, particularly functional protein microarrays, to address important questions in the field of clinical proteomics. In this review, we will summarize some of the most innovative and exciting recent applications of protein microarrays in clinical proteomics, including biomarker identification, pathogen–host interactions, and cancer biology.