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The effects of high‐frequency chest compression on end‐tidal CO 2
Author(s) -
Weiner Gabriel A.,
Forno Erick,
Weiner Daniel J.
Publication year - 2020
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.24588
Subject(s) - medicine , vest , airway , tidal volume , ventilation (architecture) , compression (physics) , cardiology , low frequency oscillation , anesthesia , respiratory system , statistics , mathematics , mechanical engineering , materials science , engineering , composite material , power (physics) , physics , electric power system , quantum mechanics
High‐frequency chest compression (HFCC) is used for airway clearance, but may have other effects. We sought to determine if HFCC provides augmented ventilation. Methods During treatment, capnometry was measured with the HFCC vest set to 6‐20 Hz. End‐tidal CO 2 (etCO 2 ) was compared using generalized estimating equations. Results Twenty‐four measurements were obtained from 15 subjects with mean age 15.2 ± 2.5 years and forced expiratory volume in one second (FEV 1 ) % predicted 70 ± 23. EtCO 2 decreased with HFCC at 6 Hz when compared with baseline ( P < .001), with small changes with increasing oscillation frequency. Change in etCO 2 was not predicted by FEV 1 , body mass index, age, or sex. Conclusions While HFCC has been shown to be a suitable method of airway clearance, investigators have failed to demonstrate differences between techniques. Assessment of these methodologies will become important as new airway clearance devices are proposed. Other outcome measures (besides FEV 1 ) may be needed to assess effects of airway clearance, and we propose that physiologic measures might be one such measure which deserves further exploration.