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Miliary tuberculosis leading to acute respiratory distress syndrome: Clinical experience in pediatric intensive care
Author(s) -
Piastra Marco,
Picconi Enzo,
Morena Tony C.,
Valentini Piero,
Buonsenso Danilo,
Conti Giorgio,
Antonelli Massimo,
Wolfler Andrea M.,
Chidini Giovanna,
PonsÒdena Martí,
De Pascale Gennaro
Publication year - 2019
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.24510
Subject(s) - medicine , miliary tuberculosis , ards , intensive care medicine , respiratory distress , respiratory failure , pediatric intensive care unit , pediatrics , intensive care unit , intensive care , tuberculosis , population , complication , lung , surgery , pathology , environmental health
Acute respiratory distress syndrome (ARDS) represents a rare complication of miliary tuberculosis (TB) in the adult setting, and it is even less common in the pediatric population. The presence of comorbidities and the possibility of a delayed diagnosis may further impair the clinical prognosis of critically ill patients with disseminated TB and acute respiratory failure. In this report, we present a case series of five pediatric patients with miliary TB and ARDS, where rescue and multimodal respiratory support strategies have been applied with a favorable outcome in more than half of them. The burden of miliary TB over time on a general pediatric intensive care unit—including two ARDS patients—is also illustrated.