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Ozone disinfection of home nebulizers effectively kills common cystic fibrosis bacterial pathogens
Author(s) -
Towle Dana,
Baker Vanisha,
Schramm Craig,
O'Brien Matthew,
Collins Melanie S.,
Feinn Richard,
Murray Thomas S.
Publication year - 2018
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.23990
Subject(s) - nebulizer , medicine , cystic fibrosis , ozone , pseudomonas aeruginosa , microbiology and biotechnology , bacteria , anesthesia , chemistry , biology , organic chemistry , genetics
Objective The Cystic Fibrosis Foundation (CFF) recommends routine nebulizer disinfection for patients but compliance is challenging due to the heavy burden of home care. SoClean® is a user friendly ozone based home disinfection device currently for home respiratory equipment. The objective of this study was to determine whether SoClean® has potential as a disinfection device for families with CF by killing CF associated bacteria without altering nebulizer output. Hypothesis Ozone based disinfection effectively kills bacterial pathogens inoculated to home nebulizer equipment without gross changes in nebulizer function. Study Design Common bacterial pathogens associated with CF were inoculated onto the PariLC® jet nebulizer and bacterial recovery compared with or without varied ozone exposure. In separate experiments, nebulizer output was estimated after repeated ozone exposure by weighing the nebulizer. Results Ozone disinfection was time dependent with a 5 min infusion time and 120 min dwell time effectively killing >99.99% bacteria tested including Pseudomonas aeruginosa and Staphylococcus aureus . Over 250 h of repeat ozone exposure did not alter nebulizer output. This suggests SoClean® has potential as a user‐friendly disinfection technique for home respiratory equipment.