Premium
Exercise capacity is not decreased in children who have undergone lung resection early in life for congenital thoracic malformations compared to healthy age‐matched children
Author(s) -
Dunn Ashlee,
Pearce Kasey,
Callister Robin,
Collison Adam,
Morten Matthew,
Mandaliya Payal,
Platt Lauren,
Dascombe Ben,
Kumar Rajendra,
Selvadurai Hiran,
Robinson Paul D.,
Mattes Joerg
Publication year - 2017
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.23772
Subject(s) - medicine , spirometry , functional residual capacity , vo2 max , lung , pulmonary function testing , lung volumes , cardiology , nitrogen washout , respiratory system , physical therapy , asthma , surgery , pediatrics , heart rate , blood pressure
Purpose The purpose of this study was to compare (i) the exercise capacity and (ii) lung function prior to and immediately post cardiopulmonary exercise tests (CPET) of children who underwent early life lung resection for Congenital Pulmonary Airway Malformations (CPAM) to healthy control children. Method Eight children with CPAM (four males, age 9.6 ± 1.8 years) and eight control children without respiratory disease (three males, age 9.4 ± 1.4 years) performed a CPET on a cycle ergometer, during which maximal oxygen consumption (V̇O 2max ) and heart rate were measured. Prior to and immediately post CPET, lung function measures including Nitrogen Multiple Breath Washout (MBW) and spirometry were performed. Results There were no significant between group differences in pre CPET lung function ( P > 0.05) or maximal exercise capacity (V̇O 2max CPAM: 39.4 mL . kg −1. min −1 , Control: 40.5 mL . kg −1. min −1 ). Post CPET, FEV 1 was significantly lower in the CPAM group, with two participants diagnosed subsequently with exercise induced bronchospasm based on post‐CPET spirometry and follow‐up clinical investigations. Conclusion Early life lung resection for CPAM does not appear to have negative implications for exercise capacity later in childhood. Clinicians should be aware that dyspnoea following exercise may be due to asthma rather than residual effects of CPAM in these children.