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Influence of intrapulmonary percussive ventilation in upright position on gastro‐oesophageal reflux in infants
Author(s) -
Van Ginderdeuren F.,
Kerckhofs E.,
Deneyer M.,
Vanlaethem S.,
Buyl R.,
Vandenplas Y.
Publication year - 2016
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.23400
Subject(s) - medicine , reflux , quartile , ventilation (architecture) , incidence (geometry) , anesthesia , gastroenterology , confidence interval , mechanical engineering , physics , disease , optics , engineering
Summary Objectives To determine the influence of physiotherapy using intrapulmonary percussive ventilation on gastro‐oesophageal reflux (GOR) in infants <1 year. Methods In this controlled trial with intra‐subject design, children were studied using multichannel intraluminal impedance pH (pH‐MII) monitoring over 24 hr, during which they received one 20‐min session of intrapulmonary percussive ventilation in upright position (IPV R ), 2 hr after their latest feeding. Two hours after each feeding, the number of reflux episodes (RE) over a 20‐min period was registered for each infant and a mean per 20 min was calculated in order to obtain a baseline value. The number of RE during IPV R intervention was compared to baseline. Results Fifty infants with a median age of 133 days were recruited of whom 21 were diagnosed with pathological GOR. During IPV R , the incidence of RE in the entire group was significantly lower compared to baseline; median (inter‐quartile range [IQR]) 0 (0–1) versus 0.71 (0–1.33) RE, respectively, P = 0.003. The subgroup with abnormal GOR showed also a significant decrease of RE during IPV R ; median (IQR) 0 (0–1) versus 1.17 (0.55–2.16) RE, respectively, P = 0.03. No difference was detected in the group with normal reflux; median (IQR) 0.6 (0–1) compared to 0 (0–1) RE, respectively, P = 0.34. Conclusion IPV R does not induce, nor aggravate GOR in infants without and with pathological GOR, respectively, but on the contrary decreases the number of RE in patients with pathological reflux. Pediatr Pulmonol. 2016;51:1065–1071. © 2016 Wiley Periodicals, Inc.