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Lung function by impulse oscillometry at age 5–7 years after bronchiolitis at age 0–6 months
Author(s) -
Lauhkonen Eero,
Koponen Petri,
Nuolivirta Kirsi,
Paassilta Marita,
Toikka Jyri,
Korppi Matti
Publication year - 2015
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.23039
Subject(s) - medicine , bronchiolitis , asthma , airway resistance , pediatrics , population , lung , respiratory system , environmental health
Summary Background Viral bronchiolitis in infancy has been associated with increased bronchial reactivity and reduced lung function in later childhood and even in adulthood. However, lung function at preschool age is less studied, mainly due to technical difficulties. The purpose of the study was to evaluate lung function and bronchial reactivity at preschool age in children who were hospitalized for bronchiolitis in early infancy. Subjects and methods Airway resistance and reactance, and bronchial reactivity to exercise were studied with impulse oscillometry (IOS) at the mean age of 6.3 years in 103 children hospitalized for bronchiolitis at less than 6 months of age. Results In baseline lung‐function measurement, resistance (n = 8; 7.8%) or reactance (19; 18.4%) at 5 Hz were pathological in 20% of children compared to Finnish population‐based height‐adjusted reference values. Increased bronchial reactivity by exercise challenge (5; 4.9%) or bronchodilatation (11; 10.7%) tests was present in 16%. Irreversible changes were revealed in only one case. Conclusions Though reduced lung function and increased airway reactivity were rather common, evidence for persistent lung function reduction was rare, less than 1%, at preschool age in children hospitalized for bronchiolitis caused mainly by respiratory syncytial virus at age less than 6 months. Pediatr Pulmonol. 2015; 50:389–395. © 2014 Wiley Periodicals, Inc.