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Symptoms of shrinking lung syndrome reveal systemic lupus erythematosus in a 12‐year‐old girl
Author(s) -
Meinicke Holger,
Heinzmann Andrea,
Geiger Julia,
Berner Reinhard,
Hufnagel Markus
Publication year - 2013
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.22704
Subject(s) - medicine , hydroxychloroquine , cyclophosphamide , lung , complication , girl , systemic lupus erythematosus , interstitial lung disease , pneumonia , systemic disease , dermatology , disease , pathology , surgery , chemotherapy , covid-19 , psychology , developmental psychology , infectious disease (medical specialty)
While pleuropulmonary involvement in systemic lupus erythematosus (SLE) is a common occurrence, shrinking lung syndrome (SLS) is a rare complication of SLE, particularly in children. We report on a teenager girl with a primary SLE diagnosis, which was based upon clinical, imaging, lung‐function and histological findings ascertained to be compatible with SLS. Following a pneumonia, the patient developed inflammatory residues in the lower lobes, an event that probably caused diaphragmatic immobility and subsequently led to SLS. Treatment response to steroids, cyclophosphamide and hydroxychloroquine in this case was excellent, and efficacy was more profound than previously has been reported in the literature with respect to pediatric patients. This case report argues that prognosis of SLS in SLE is likely to be favorable when the diagnosis is made early and the disease is treated appropriately. Pediatr Pulmonol. 2013; 48:1246–1249. © 2012 Wiley Periodicals, Inc.