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Invasive pneumonia and septic shock in infants as a presentation of cystic fibrosis with vitamin‐deficiency
Author(s) -
AlKhadra Eman S.,
Chau Kinwai,
Barone Cara Pizzo,
Colin Andrew A.
Publication year - 2012
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.21611
Subject(s) - medicine , cystic fibrosis , pneumonia , presentation (obstetrics) , septic shock , pseudomonas aeruginosa , pediatrics , intensive care medicine , regimen , immunology , sepsis , surgery , biology , bacteria , genetics
Abstract Herein we describe three infants with the rare presentation of pneumonia with septic shock as their initial medical encounter leading to the diagnosis of cystic fibrosis (CF). At the time of their presentation all three children had significant nutritional deficiency. We initiated an aggressive treatment regimen including nutritional supplementation which resulted in improvement in their pulmonary status and no further recurrences. This series highlights the possible presentation of CF in infancy as a life‐threatening invasive infection of Staphylococcus aureus or Pseudomonas aeruginosa . It also supports neonatal screening and emphasizes the role of early attention to nutritional status and vitamin supplementation. Pediatr Pulmonol. 2012; 47:722–726. © 2011 Wiley Periodicals, Inc.