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Plastic bronchitis as an unusual cause of mucus plugging in cystic fibrosis
Author(s) -
MateosCorral Dimas,
Cutz Ernest,
Solomon Melinda,
Ratjen Felix
Publication year - 2009
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.21063
Subject(s) - cystic fibrosis , medicine , mucus , sputum , etiology , bronchitis , airway obstruction , airway , pathology , fibrosis , chronic bronchitis , surgery , tuberculosis , biology , ecology
Cystic fibrosis patients are known to produce abundant, purulent sputum consisting mainly of DNA and cellular debris. We present a case of a CF patient with recurrent airway obstruction caused by a rare condition known as plastic bronchitis (PB). PB is characterized by the formation of casts of the airways that cause obstruction. Multiple etiologies have been proposed, but to our knowledge, no CF patient has been reported in any PB classification. Histological analysis and in‐vitro testing of the cast were important factors in choosing the adequate therapy in this patient. Pediatr Pulmonol. 2009; 44:939–940. © 2009 Wiley‐Liss, Inc.