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Lung resection in cystic fibrosis: A survival analysis
Author(s) -
Camargos Paulo,
Le Bourgeois Muriel,
Revillon Yann,
Tatsuo Edson,
SermetGaudelus Isabelle,
Scheinmann Pierre,
de Blic Jacques
Publication year - 2008
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.20742
Subject(s) - medicine , bronchiectasis , atelectasis , surgery , lung , cystic fibrosis , pneumonectomy , survival analysis , resection , refractory (planetary science) , survival rate , respiratory disease , physics , astrobiology
Lung resection may be considered for cystic fibrosis (CF) patients showing localized severe chronic atelectasis and/or bronchiectasis. Nonetheless, literature on survival after surgery is scarce. This study was carried out to assess survival time after partial lung resection. Twenty‐one CF patients were operated from 1988 to 2003 and were followed until November 30th, 2004. Survival analysis was performed through Kaplan–Meier method. Mean age at resection was 8.09 years (SD 4.40 years) and two‐thirds were females. Z ‐scores for height, weight, and body mass index as well as FEV 1 values showed no statistical significance when comparing values obtained from 2 years before to 2 years after resection. Eleven years after resection, survival probability was 93.8%. Our results suggest that lobectomy or segmentectomy are safe procedures and should be considered in carefully selected patients with unilateral severe symptomatic localized and chronic persistent atelectasis and/or bronchiectasis refractory to conservative management. Pediatr Pulmonol. 2008; 43:72–76. © 2007 Wiley‐Liss, Inc.