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Persistent respiratory symptom can be a manifestation of neurofibromatosis‐1
Author(s) -
Saha Agni S.,
Tuladhar Anil,
Mitchell Leslie,
Spencer David
Publication year - 2006
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.20426
Subject(s) - medicine , neurofibromatosis , respiratory system , respiratory disease , pediatrics , dermatology , intensive care medicine , pathology , lung
A 3‐year old boy with Neurofibromatosis‐1 presented with persistent respiratory symptoms and X‐ray changes. High resolution Computerised Tomography (CT), bronchoscopy and spiral CT showed a mediastinal mass encasing and compressing the left main stem bronchus. Surgical removal and histology of the mass revealed a neurofibroma. Repeat scan six months post‐surgery showed some persistence of the mass. Symptomatic, mediastinal neurofibroma in the Paediatric age group is very rare. We could not find any previous report of a neurofibroma encasing the mediastinal structures. This case also demonstrates that persistent respiratory symptom in a patient with Neurofibromatosis‐1 warrants a search for intra‐thoracic Neurofibroma. Pediatr Pulmonol. 2006; 41: 796–797. © 2006 Wiley‐Liss, Inc.