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Lung‐function tests in neonates and infants with chronic lung disease: Tidal breathing and respiratory control
Author(s) -
Baldwin David N.,
Pillow J. Jane,
Stocks Janet,
Frey Urs
Publication year - 2006
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.20400
Subject(s) - medicine , breathing , lung disease , apnea , control of respiration , respiratory disease , lung , tidal volume , respiratory system , respiratory physiology , intensive care medicine , pediatrics , cardiology , anesthesia
This paper is the fourth in a series of reviews that will summarize available data and critically discuss the potential role of lung‐function testing in infants with acute neonatal respiratory disorders and chronic lung disease of infancy. The current paper addresses information derived from tidal breathing measurements within the framework outlined in the introductory paper of this series, with particular reference to how these measurements inform on control of breathing. Infants with acute and chronic respiratory illness demonstrate differences in tidal breathing and its control that are of clinical consequence and can be measured objectively. The increased incidence of significant apnea in preterm infants and infants with chronic lung disease, together with the reportedly increased risk of sudden unexplained death within the latter group, suggests that control of breathing is affected by both maturation and disease. Clinical observations are supported by formal comparison of tidal breathing parameters and control of breathing indices in the research setting. Pediatr Pulmonol. 2006; 41:391–419. © 2006 Wiley‐Liss, Inc.