Persistent pulmonary hypertension of newborn due to congenital capillary alveolar dysplasia | Zendy

Singh Soraisham Amuchou | Zendy; Ibrahim Thowfique | Zendy; Clark Deborah Jane | Zendy; Taylor Richard Scott | Zendy; George David Hilles | Zendy

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Persistent pulmonary hypertension of newborn due to congenital capillary alveolar dysplasia

Author(s) -

Singh Soraisham Amuchou,

Ibrahim Thowfique,

Clark Deborah Jane,

Taylor Richard Scott,

George David Hilles

Publication year - 2005

Publication title -

pediatric pulmonology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.866

H-Index - 106

eISSN - 1099-0496

pISSN - 8755-6863

DOI - 10.1002/ppul.20244

Subject(s) - medicine , bronchopulmonary dysplasia , persistent pulmonary hypertension , pulmonary hypertension , autopsy , pathophysiology , dysplasia , pathology , pediatrics , cardiology , pregnancy , genetics , biology , gestational age

Congenital alveolar capillary dysplasia is a rare and fatal cause of pulmonary hypertension in neonates. We report on a term baby with severe pulmonary hypertension unresponsive to high‐frequency ventilation and nitric oxide. A diagnosis of alveolar capillary dysplasia was established on autopsy. We review the literature regarding pathophysiology, clinical presentations, associated malformations, and treatment trials. Pediatr Pulmonol. © 2005 Wiley‐Liss, Inc.

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