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Acute hypoxic respiratory failure as the first manifestation of systemic‐onset juvenile rheumatoid arthritis in a child
Author(s) -
Rochat Isabelle,
Sayegh Yasmine,
Gervaix Alain,
Rimensberger Peter C.,
Argiroffo Constance Barazzone
Publication year - 2004
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.20107
Subject(s) - medicine , juvenile rheumatoid arthritis , rheumatoid arthritis , respiratory failure , arthritis , methylprednisolone , systemic disease , leflunomide , respiratory system , juvenile , pediatrics , disease , biology , genetics
Systemic onset juvenile rheumatoid arthritis is the most common rheumatologic disorder of childhood. Pleuropulmonary manifestations are rare in children in this multiorgan disease, and are usually not severe. The diagnosis of systemic onset juvenile rheumatoid arthritis is made by exclusion, in the presence of clinical findings constellation. We present the case of an 8‐year‐old girl who developed acute hypoxic respiratory failure as the first manifestation of systemic onset juvenile rheumatoid arthritis, then severe respiratory relapse 16 months later. Clinical and radiological improvement were achieved at both times after high dose pulse methylprednisolone therapy. © 2004 Wiley‐Liss, Inc.