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Clinical lessons from an experimental model of ARDS
Author(s) -
Schuster Daniel P.
Publication year - 1995
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950191151
Subject(s) - ards , medicine , acute respiratory distress , intensive care medicine , animal model , pathogenesis , pathophysiology , pulmonary injury , lung , pathology , pulmonary fibrosis
The oleic acid (OA) lung injury model is one of the most common laboratory methods for studying the acute respiratory distress syndrome (ARDS) in experimental animals. Many features of the model mimic the pathophysiology of ARDS in humans, despite obvious differences in pathogenesis. Thus, the OA lung injury model has been used extensively to study the consequence of lung injury and to evaluate potential new treatment strategies. © 1995 Wiley‐Liss, Inc.