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Continuous positive airway pressure by nasal prongs in bronchiolitis
Author(s) -
Soong WenJue,
Hwang Betau,
Tang RenBin
Publication year - 1993
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950160305
Subject(s) - medicine , bronchiolitis , anesthesia , continuous positive airway pressure , arterial blood , mean airway pressure , respiratory rate , respiratory system , ventilation (architecture) , oxygenation , peak inspiratory pressure , heart rate , mean arterial pressure , blood pressure , mechanical ventilation , tidal volume , mechanical engineering , obstructive sleep apnea , engineering
Ten infants with evidence of impending respiratory failure from severe bronchiolitis were successfully treated with continuous positive airway pressure (NCPAP) with double nasal prongs. Their mean (SD) age was 6.7 (3.8) months and mean (SD) body weight was 7.1 (2.1) kg. Respiratory assessments were made immediately before and 2 hours after application of NCPAP. Clinical symptoms, signs, and arterial blood gases improved in all patients, with a significant fall in mean (SD) respiratory rate [71 (6) vs. 54 (9) per minute], mean (SD) heart rate (178 (9) vs. 154 (15) per minute], and mean (SD) partial pressure of arterial carbon dioxide (Pa co 2; 48.0 (13.9) vs. 42.4 (12.9) mmHg]. There was a significant rise in mean (SD) arterial blood pH 33 (0.05) vs. 7.37 (0.05)) and mean (SD) oxygenation ratio [Fi o2 /Pa o2 , 155 (25) vs. 175 (22)]. We believe NCPAP is an effective method, with numerous advantages in the treatment of severe bronchiolitis. Early application of NCPAP is suggested to avoid the need for mechanical ventilation. Pediatr Pulmonol. 1993; 16:163–166. © 1993 Wiley‐Liss, Inc.