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Association between pulmonary and gastric inflammatory cells on the first day of life in preterm infants
Author(s) -
Ar Shmuel,
Grigg Jonathan,
Silverman Michael
Publication year - 1993
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950160112
Subject(s) - medicine , bronchoalveolar lavage , amniotic fluid , fetus , respiratory disease , lung , pneumonitis , gastroenterology , pregnancy , obstetrics , biology , genetics
It has been shown that inflammatory cells in the newborn lung are fetal in origin, whereas those in the amniotic fluid are maternal. In order to explore the relationship between fetal amnionitis and neonatal pneumonitis, we collected paired samples of gastric aspirate within 2 hours of birth, and bronchoalveolar lavage fluid within 24 hours of birth from intubated preterm infants. Leukocyte counts in bronchoalveolar lavage fluid correlated with the duration of membrane rupture ( r = 0.68, P = 0.0001). There was a high degree of correlation between leukocyte counts in the two fluids ( r = 0.86, P = 0.0001). The factors responsible for this association are unknown. Pediatr Pulmonol. 1993; 16:59–61. © 1993 Wiley‐Liss, Inc.