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Transcutaneous and arterial blood gas monitoring during acute asthmatic symptoms in older children
Author(s) -
Holmgren D.,
Sixt R.
Publication year - 1992
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950140204
Subject(s) - medicine , salbutamol , inhalation , arterial blood , anesthesia , asthma , bronchodilator , blood flow , cardiology
The relationship between transcutaneous and arterial blood gases was investigated in 14 children with asthmatic symptoms, aged 7–15 years, before and after the inhalation of salbutamol. The degree of bronchial obstruction was assessed by forced expiratory volume in one second (FEV 1 ) and maximum expiratory flow when 25% of FVC remained to be expelled (MEF 25 ). On average the transcutaneous P o 2 (tcP o 2,) was 1.3 kPa (range, 2.6–0 kPa) lower and the transcutaneous P co 2 was 0.6 kPa (range, 0–1.5 kPa) higher than the corresponding arterial values ( P < 0.01). The difference between arterial and transcutaneous P o 2, was the same over the whole range of values studied (7.5–14 kPa). After the inhalation of salbutamol, the relationship between transcutaneous and arterial blood gases was not significantly changed. Changes in transcutaneous P o 2 correlated to changes in MEF 25 ( P < 0.05). indicating a common denominator, probably the conditions in the peripheral airways. We conclude that the close relationship between transcutaneous and arterial blood gases, even after the inhalation of a beta‐2 agonist, indicates that the transcutaneous technique can be used for monitoring acute bronchial obstruction and for evaluating the effects of treatment in children of different ages. © 1992 Wiley‐Liss, Inc.