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Use of a touch sensitive screen and computer assisted image analysis for quantitation of developmental changes in pulmonary structure
Author(s) -
Deoras Kiran S.,
Wolfson Marla R.,
Searls Robert L.,
Hilfer S. Robert,
Sheffield Joel B.,
Shaffer Thomas H.
Publication year - 1990
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950090208
Subject(s) - medicine , pulmonary function testing , respiratory system , respiratory physiology , pulmonary medicine , pathology , function (biology) , biomedical engineering , anatomy , radiology , intensive care medicine , biology , evolutionary biology
The extensive changes in pulmonary function occurring during early development may reflect variations in the anatomic structure of the respiratory apparatus during this period. Accurate definition of these alterations could yield important information concerning the structure‐function correlations of the respiratory system. To facilitate the acquisition of morphometric data from histologic sections of pulmonary tissues, we propose the use of a computer assisted image analysis system with a touch sensitive screen as an interactive peripheral. This allows planimetric measurements and computation of the dimensions of areas of selected light intensities within an image. We present the description, design, and applications of such an image analysis system and report representative results regarding developmental changes in pulmonary structure. In addition, we correlate these results with previously published information regarding pulmonary mechanics during early development to help clarify the maturational changes in pulmonary structure‐function relationships. Pediatr Pulmonal 1990; 9:109–118 .