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Pulmonary function following mild respiratory tract infections (“common cold”) in teenagers
Author(s) -
Teculescu Dan B.,
Pham Quang Thieu,
Chau Nearkasèn,
Aubry Catherine,
Kuntz Claude
Publication year - 1988
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950050404
Subject(s) - medicine , vital capacity , pulmonary function testing , lung volumes , respiratory tract , respiratory system , lung function , lung , respiratory tract infections , abnormality , respiratory physiology , cardiology , diffusing capacity , psychiatry
Ventilatory function—forced vital capacity (VC)—forced expiratory volume (in 1‐sec forced expiratory flows) static lung volumes, closing volume, and phase III slope (singlebreath N 2 test) were compared in 94 children with and 436 children without a history of recent mild acute respiratory infection. Their age ranged from 10 to 16 years; subjects with symptoms on the day of the study were excluded. We found no difference in lung function between the two groups, with the exception of a slight (inconsistently significant) increase in closing volume (CV) and the CV/VC ratio. Although the influence of a persistent increase in interstitial lung pressure leading to early small airways closure cannot be ruled out, this isolated functional abnormality probably represents a spurious positive result, arising by chance when a large number of statistical tests are done.