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Effect of sleep state on chest wall movements and gas exchange in infants with resolving bronchopulmonary dysplasia
Author(s) -
Rome Ellen S.,
Miller Martha J.,
Goldthwait David A.,
Osorio Ivan O.,
Fanaroff Avroy A.,
Martin Richard J.
Publication year - 1987
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950030412
Subject(s) - medicine , bronchopulmonary dysplasia , anesthesia , sleep (system call) , pediatrics , gestational age , pregnancy , genetics , computer science , biology , operating system
During active sleep, neonates exhibit asynchronous chest wall movements, which have been associated with a small but significant decrease in oxygenation. To determine the effects of maturation and residual chronic lung disease on both these phenomena, we studied 11 preterm infants with resolving bronchopulmonary dysplasia (BPD) and compared these infants to ten healthy preterm infants all at time of discharge. Synchrony of chest wall (upper rib cage and abdominal) movements, sleep state, O 2 saturation, and transcutaneous CO 2 (TcP co 2 ) were recorded during both active (AS) and quiet sleep (QS). Sleep state was determined by electroencephalographic and behavioral criteria. Normal preterm infants displayed asynchronous chest wall movements only in AS, whereas, in infants with BPD, asynchrony predominated in both sleep states, although O 2 saturation and TcP co 2 did not differ between sleep states in either group. The O 2 saturation during AS was lower in the BPD group than in the group of normal infants (92% vs 96%; P < 0.02), whereas TcP co 2 was higher in the BPD group unrelated to sleep state. We conclude that infants with resolving BPD exhibit asynchronous chest wall movements in both AS and QS, and that change in sleep state from QS to AS is not associated with a detrimental fall in oxygenation in these infants.