Premium
Clinical observations on mechanical ventilation for respiratory failure in bronchiolitis
Author(s) -
Frankel Lorry R.,
Lewiston Norman J.,
Smith David W.,
Stevenson David K.
Publication year - 1986
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950020511
Subject(s) - medicine , bronchiolitis , mechanical ventilation , respiratory system , respiratory failure , pneumothorax , ventilation (architecture) , respiratory disease , pneumonia , anesthesia , lung , surgery , mechanical engineering , engineering
An unusually large number of infants (82) were admitted to Stanford University Hospital from November 1,1983, through May 31,1985, with a diagnosis of bronchiolitis requiring oxygen therapy. A larger percentage of these infants (17/82 = 21%) than generally expected required mechanical ventilation for respiratory failure. Fourteen infants had respiratory syncytial virus (RSV) infections, and three had parainfluenza virus infections. Ten patients had respiratory difficulties as neonates. The mechanical ventilation of the children requiring respiratory assistance was characterized by high minute ventilation with high tidal volumes (15 to 20 ml/kg) and slow respiratory rates (16 to 22 breaths/min). Peak inspiratory pressure averaged (mean ± SD) 35 ± 6 cm H 2 O in the RSV group and 34 ± 6 cm H 2 O in the parainfluenza group. The mean number of days on the ventilator was 9.7 ± 3.1 for the RSV group and 8.3 ± 2.9 for the parainfluenza group. All were extubated within 17 days of presentation and discharged within 28 days. The complications encountered included pneumothorax and acute pulmonary hypertension.