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Breast feeding and maternal smoking as predictors of wheezing in children age 6 to 10 years
Author(s) -
McConnochie Kenneth M.,
Roghmann Klaus J.
Publication year - 1986
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950020503
Subject(s) - medicine , asthma , odds ratio , family history , breast feeding , respiratory sounds , allergy , passive smoking , pediatrics , cohort , odds , immunology , logistic regression , environmental health
The possibility that controllable environmental factors such as passive smoking and non‐breast feeding contribute substantially to wheezing has implications for prevention. Effects of passive smoking and non‐breast feeding on wheezing in children aged 6 to 10 years were explored in a historical cohort study of 223 children. Family history of respiratory allergy or asthma, male sex, maternal smoking, and non‐breast feeding were significantly associated (p < 0.05) with wheezing in bivariate analysis. In multivariate loglinear analyses, predictors of wheezing included non‐breast feeding (p = 0.05, odds ration = 2.1), male sex (p< 0.03, odds ratio = 3.1), and family history of respiratory allergy (p < 0.03, odds ratio = 2.6). In a second model, predictors included an interaction of maternal smoking and family history (p < 0.005, odds ratio = 4.6) in addition to male sex and family history of respiratory allergy. In further exploration based on tabular analysis, maternal smoking appeared to increase wheezing among children in whom the family history of respiratory allergy was positive (p < 0.001). Among children in whom the family history of respiratory allergy was negative, non‐breast feeding appeared to increase wheezing (p = 0.01). Promotion of breast feeding and reduction of maternal smoking might reduce childhood wheezing.