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Bronchodilator response during acute viral bronchiolitis in infancy
Author(s) -
Soto Manuel E.,
Sly Peter D.,
Uren Eric,
Taussig Lynn M.,
Landau Louis I.
Publication year - 1985
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.1950010206
Subject(s) - medicine , bronchiolitis , bronchodilator , bronchodilator agents , acute bronchiolitis , intensive care medicine , pediatrics , asthma , immunology , virus
Bronchodilator responsiveness was assessed by measuring specific respiratory conductance before and after inhalation of aerosolized bronchodilator in 50 infants who had acute bronchiolitis due to respiratory syncytial virus infection. Thirty per cent of the infants showed an improvement in specific conductance. Responders could not be differentiated from nonresponders by family histories of atopy, eosinophil counts, or immunoglobulin levels in blood and nasal secretions. Eighty‐three per cent of the families and 54% of the mothers of the infants were smokers. Babies of smoking mothers had lower specific conductances than did those of nonsmoking mothers but showed no differences in bronchodilator response. The clinical significance of this bronchodilator‐responsive subgroup has yet to be defined.