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Adrenal insufficiency and testicular failure secondary to megestrol acetate therapy in a patient with cystic fibrosis
Author(s) -
McKone Edward F.,
Tonelli Mark R.,
Aitken Moira L.
Publication year - 2002
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.10184
Subject(s) - megestrol acetate , medicine , cystic fibrosis , adrenal insufficiency , megestrol , adverse effect , gastroenterology , surgery , cancer
We present a case report of adrenal insufficiency and testicular failure in an adult cystic fibrosis (CF) patient due to megestrol acetate therapy. This is followed by a review of the literature on the use of megestrol acetate in the treatment of weight loss in CF, AIDS, and cancer, with particular emphasis on the adverse effects that should be looked for in CF patients. Pediatr Pulmonol. 2002; 34:381–383. © 2002 Wiley‐Liss, Inc.