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Cystic fibrosis and infantile hypertrophic pyloric stenosis: Is there an association?
Author(s) -
Kakish Khalid S.
Publication year - 2002
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.10089
Subject(s) - medicine , cystic fibrosis , hypertrophic pyloric stenosis , incidence (geometry) , population , pediatrics , pyloric stenosis , gastroenterology , stenosis , physics , environmental health , optics
Cystic fibrosis (CF) is the most common lethal genetic disease among Caucasian populations. The generally accepted incidence of CF in the United States is 1 in 3,200 in the Caucasian population. Intestinal obstructions and atresias have been described among patients with CF. An association of CF with infantile hypertrophic pyloric stenosis (IHPS) has not been previously documented. A review in our clinic of 72 patients with CF revealed IHPS in two. The incidence of 2.7% is greater than the 0.3% incidence expected in the general population. This ninefold increase in IHPS in patients with CF suggests an association between the two and warrants further investigation. Pediatr Pulmonol. 2002; 33:404–405. © 2002 Wiley‐Liss, Inc.