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Subcutaneous terbutaline in children with chronic severe asthma *
Author(s) -
Payne Donald N.R.,
BalfourLynn Ian M.,
Biggart Elizabeth A.,
Bush Andrew,
Rosenthal Mark
Publication year - 2002
Publication title -
pediatric pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.866
H-Index - 106
eISSN - 1099-0496
pISSN - 8755-6863
DOI - 10.1002/ppul.10081
Subject(s) - medicine , terbutaline , asthma , pediatrics , prednisolone , anesthesia
A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone. Five patients experienced a symptomatic improvement from CSIT, leading to a reduction in regular medication. Three patients did not experience any lasting benefit from CSIT. The most common side effects were related to the infusion site (bruising and local infection). CSIT may lead to an improvement in symptoms and a reduction in oral steroid dose in selected children with chronic severe asthma. These initial findings support the need for further controlled studies to evaluate the use of CSIT in severe childhood asthma. Pediatr Pulmonol. 2002; 33:356–361. © 2002 Wiley‐Liss, Inc.