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In Situ Self‐Assembly of Quantum Dots at the Plasma Membrane Mediates Energy Transfer‐Based Activation of Channelrhodopsin (Part. Part. Syst. Charact. 7/2021)
Author(s) -
Nag Okhil K.,
Muroski Megan E.,
Field Lauren D.,
Stewart Michael H.,
Oh Eunkeu,
Susumu Kimihiro,
Spangler Joseph R.,
Walper Scott A.,
Delehanty James B.
Publication year - 2021
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.202170014
Subject(s) - channelrhodopsin , photoexcitation , quantum dot , photoisomerization , ion channel , chemistry , energy transfer , ion , optogenetics , optoelectronics , nanotechnology , photochemistry , materials science , isomerization , chemical physics , excited state , physics , receptor , atomic physics , biochemistry , organic chemistry , neuroscience , biology , catalysis
In article 2100053, Delehanty and co‐workers describe an energy transfer system for the indirect activation of channelrhodopsin ion channels. A light‐harvesting quantum dot (QD) nanoparticle is self‐assembled to the exofacial domain of the ion channel. Upon photoexcitation, the QD transfers energy to the retinal moiety in the ion channel, resulting in its photoisomerization and channel opening.