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Nanotoxicity: Harnessing Calcium‐Oxalate‐ (CaOx‐) Nanocrystal‐Induced Prodeath Autophagy for Attenuating Human Renal Proximal Tubular Epithelial Cell Injury (Part. Part. Syst. Charact. 8/2019)
Author(s) -
Chen Yang,
Wei Pengfei,
Meng Jialin,
Fan Song,
Zhang Yanbin,
Xi Junhua,
Liang Chaozhao,
Zhang Li,
Hao Zongyao
Publication year - 2019
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201970022
Subject(s) - autophagy , calcium oxalate , nanocrystal , calcium , chemistry , microbiology and biotechnology , apoptosis , cell , programmed cell death , cancer research , nanotechnology , materials science , medicine , biochemistry , biology , organic chemistry
In article number 1900083, Chaozhao Liang, Li Zhang, Zongyao Hao, and co‐workers prepare calcium oxalate nanocrystals (CaOx NCs) from clinical samples through ball milling. These CaOx NCs induce prodeath autophagy and autophagy‐modulated apoptosis to cause toxicity. Harnessing autophagy could efficiently attenuate kidney cell injury.