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Controlled Drug Release: Magnesium Particles Coated with Mesoporous Nanoshells as Sustainable Therapeutic‐Hydrogen Suppliers to Scavenge Continuously Generated Hydroxyl Radicals in Long Term (Part. Part. Syst. Charact. 2/2019)
Author(s) -
Kong Lei,
Chen Chuanrui,
Mou Fangzhi,
Feng Yizheng,
You Ming,
Yin Yixia,
Guan Jianguo
Publication year - 2019
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201970006
Subject(s) - nanoshell , radical , mesoporous material , magnesium , controlled release , materials science , hydrogen , drug , chemistry , chemical engineering , nanotechnology , nanoparticle , organic chemistry , pharmacology , catalysis , medicine , engineering
As demonstrated by Lei Kong, Fangzhi Mou, Jianguo Guan and co‐workers in article number 1800424 , magnesium microparticles coated with mesoporous SiO 2 nanoshells show high‐efficient generation of vast quantities of therapeutic hydrogen in physiological condition with a rate controlled by the nanoshell thickness, and thus can eliminate excessive hydroxyl radicals in vivo over a long period.