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Biosensors: Adamantane Derivatives Functionalized Gold Nanoparticles for Colorimetric Detection of MiRNA (Part. Part. Syst. Charact. 6/2017)
Author(s) -
Miao Peng,
Tang Yuguo,
Mao Zhiqing,
Liu Yuanzhong
Publication year - 2017
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201770019
Subject(s) - adamantane , colloidal gold , biosensor , combinatorial chemistry , nanotechnology , nanoparticle , chemistry , dna , materials science , organic chemistry , biochemistry
As described by Peng Miao, Yuguo Tang, and co‐workers in article number 1600405 , adamantane derivatives functionalized gold nanoparticles act as a novel platform for colorimetric biosensing. By further modification with designed DNA probes, strand displacement amplification, triggered by target miRNA, is achieved, leading to massive aggregation of gold nanoparticles. The approach shows promise for amplified detection of miRNA in biological samples.